Cardiac contractility modulation, or CCMTM therapy, may be an option for people who aren’t adequately responding to heart failure medications.1

As heart failure progresses, the heart slowly weakens and is not able to pump with the force required to supply oxygen-rich blood to meet the body’s needs. Symptoms can make everyday activities, such as walking, challenging. They include breathlessness, fatigue, confusion and swelling in the legs. Most people are prescribed medications intended to slow the progression of the disease and manage their symptoms. As the condition progresses, these medications lose their effectiveness and the quality of life for people with heart failure continues to decline.

CCM therapy has been proven to be safe and effective in numerous clinical studies, including several randomized controlled trials, and the results have been published in more than 80 articles in leading medical journals.2

How It Works 

The Optimizer device is similar in size to a pacemaker that is implanted during a minimally invasive procedure while the patient is under light sedation.

During the procedure, the device is implanted under the skin of the upper chest, along with electrical leads that are placed in the heart’s right ventricle through the veins (transcatheter).

After the procedure, the physician programs the delivery of CCM® therapy for each patient and activates the device. The implanted device then sends electrical pulses to the heart muscle for a total of five hours a day, in one-hour treatments separated by regular intervals.

From the comfort of home, the patient charges the device each week for one hour using an external charger. The Optimizer has been rigorously tested and it is expected to provide CCM® therapy for up to 15 years before requiring replacement.

Frequently Asked Questions

Marshall Cardiology - Huntington

A provider-based department of Cabell Huntington Hospital
Erma Ora Byrd Clinical Center
1249 15th Street
Fourth Floor
Huntington, WV 25701
Phone: 304.691.8500

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1 Abraham WT, Kuck KH, Goldsmith RL, et al. A randomized controlled trial to evaluate the safety and efficacy of cardiac contractility modulation. JACC Heart Failure. 6(10), 874-883 (2018).
2 Clinical evidence on file: